Optimizing Exercise as Therapy in Cardiopulmonary Disease

Publications

A complete list of Dr. Brown’s publications can be found at this link:

https://www.ncbi.nlm.nih.gov/myncbi/1Fkmwas8bmyQ7x/bibliography/public/

Cover of Pulmonary Circulation

In the article by Brown MB, Kempf A, Collins C, Long G, Gupta S, Hellman Y, Wong V, Farber M, Lahm T titled ‘A Prescribed Walking Regimen plus Arginine Supplementation Improves Function and Quality of Life for Patients with Pulmonary Arterial Hypertension:  A Pilot Study’ published in the journal Pulmonary Circulation 2017; 8(1) 1–12. DOI: 10.1177/2045893217743966, Dr. Brown and colleagues determined for the first time that a mostly home-based exercise program was feasible and effective for patients with pulmonary arterial hypertension.

Cover of American Journal of Physiology

In the article by Brown MB, Neves E, Long G, Novack R, Graber J, Gladish B, Owens M, Wiseman A, Fisher A, Presson R, Petrache I, Kline J, Lahm T titled ‘High Intensity Interval Training (HIIT) but not Continuous Training Reverses Right Ventricular Remodeling and Dysfunction in a Rat Model of Pulmonary Arterial Hypertension’ published in the journal  Am J Physiol Reg Int Comp Physiol. 2017 Feb 1;312(2): R197-R210 doi:10.1152/ajpregu.00358.2016; Dr. Brown and colleagues determined that a HIIT approach to exercise training was more effective than a continuous approach for rats with a mild form of experimentally-induced pulmonary hypertension.